San Francisco 49ers vs. Los Angeles Rams 9/22/24 – At this point in the NFL Week 3, the San Francisco 49ers (1-1) are taking on the Los Angeles Rams (0-2) in what promises to be a thrilling encounter at SoFi Stadium on Sunday. The focus of the battle is also the early-season momentum, and hence, the stakes are pretty high, especially for the L.A. Rams, who are looking to avoid a third consecutive loss. The 49ers want to improve on the good start they have had, whereas the Rams have to win a game for the first time this season. Do not miss all the football latest free prediction on this exciting NFC West duel.
San Francisco 49ers vs. Los Angeles Rams 9/22/24
| When: | Sunday, September 22, 2024 at 4:25 PM ET |
|---|---|
| Where: | SoFi Stadium |
| TV: | FOX |
| Stream: | NFL Game Pass |
| Team | SP/RL | TOTAL | ML | |
|---|---|---|---|---|
| 49ers | -4 (-120) | 46.5 over (-120) | -180 |  |
| Rams | +4 (-120) | 46.5 under (-120) | +152 | |
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At the moment, the betting odds are giving the 49ers the edge over their opponents by a spread of 4, which means that they are believed to be able to dictate the game more so than the Rams, who, to avoid the embarrassment of not winning at all, are fighting for their lives. The over/under is 46.5, which means that the scores coming from the two sides will not be low, considering the attacking prowess and weak defense observed, considering that the season is just starting.
Brock Purdy vs. Matthew Stafford
Brock Purdy of the San Francisco 49ers has demonstrated composure and decision-making inside the pocket during the first two matches. Purdy’s performance has been impressive, throwing at 72.3 completion percentages for 550 yards with one touchdown and one interception. It will be important against the Rams, who have a powerful defensive line, as he has been sacked eight times already.
At the same time, on the other side of the field, veteran Matthew Stafford is heading the Rams as well, recording similar statistics with 533 yards throwing and a 69.7% completion rate. Although his statistics were not impressive regarding touchdowns, twenty-four touchdown passes, and an ideal completion score, year placement is a critical challenge for him. For the first time in the season, the Rams will seek this veteran quarterback’s skills to get them a coveted win.
Ground and Air Assault: San Francisco’s Dynamic Offense
Jordan Mason and Jauan Jennings are pivotal in the 49ers’ offensive scheme. Mason, with 247 rushing yards and an impressive average of 5.1 yards per carry, is a breakout star who brings explosive power and agility to the ground game. His ability to rip through defenses is complemented by Jennings’ reliable hands and route-running precision. Jennings, although yet to find the end zone, has amassed 101 receiving yards and maintains a crucial role in moving the chains on critical downs.
Rams’ Response: A Struggle for Consistency
For the Rams, Kyren Williams and Cooper Kupp are the key figures in their offensive playbook. Williams, although only averaging 2.5 yards per carry, has shown flashes of potential and needs to find more consistent gaps. Meanwhile, Kupp remains Stafford’s favorite target, securing 18 catches for 147 yards. His knack for making pivotal plays will be indispensable for the Rams as they aim to upset the 49ers.
Trends
San Francisco 49ers Betting Trends
- San Francisco are 1-5 ATS in their last 6 games.
- The total has gone OVER in 8 of San Francisco’s last 12 games.
- San Francisco are 10-4 SU in their last 14 games.
- 49ers are 7-2 ATS in their last 9 games against LA Rams.
- San Francisco are 9-2 SU in their last 11 games against LA Rams.
Los Angeles Rams Betting Trends
- LA Rams are 7-3 ATS in their last 10 games.
- The total has gone OVER in 7 of LA Rams’ last 10 games.
- The total has gone OVER in 4 of LA Rams’ last 6 games against San Francisco.
- LA Rams are 5-1 SU in their last 6 games at home.
- LA Rams are 1-5 ATS in their last 6 games when playing at home against San Francisco.
San Francisco 49ers vs. Los Angeles Rams Betting Prediction
Considering their history head-to-head and their performance metrics, the 49ers are most likely going to beat the Rams in this contest. Nevertheless, the Rams’ dire circumstances and the home court might fuel an upset. The 49ers are trustworthy enough to beat the spread, at the same time considering taking the OVER, due to the nature of both teams to score many points.
As we conclude our selections, it is clear that this game is most suited for intelligent wagering. The 49ers seem to be the preferable team because they are more consistent and have a better record in the past, however, the potential of the Rams breaking out, particularly in their comfort zone, makes it an attractive underdog selection. This is why one should always place their bets at the best sportsbook online for the best odds and game day experience as well.
Score Prediction: 49ers 27, Rams 21.
Hilbert Mayer
Sports Writer
Hilbert Mayer is a professional sports writer, betting analyst, and content strategist with over 15 years of experience in the sports industry. Before focusing on sports betting analysis and handicapping, Hilbert worked as a sports writer for various news outlets, covering everything from game recaps to in-depth matchup features. Today, he specializes in MLB, NFL, March Madness, and UFC betting, combining his journalistic background with deep statistical expertise and real-world betting insights. His proven track record, sharp reads, and ability to break down complex matchups make him a trusted voice among both casual bettors and seasoned sharps.
Published on: September 19, 2024
Last updated: March 26, 2025