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Home » NCAA Bets: Top College Football Betting Online » Louisville Cardinals vs. Notre Dame Fighting Irish 9/28/24 NCAAF Week 5 Betting Prediction

Louisville Cardinals vs. Notre Dame Fighting Irish 9/28/24 NCAAF Week 5 Betting Prediction

Louisville Cardinals vs. Notre Dame Fighting Irish 9/28/24 NCAAF Week 5 Betting Prediction

Louisville Cardinals vs. Notre Dame Fighting Irish 9/28/24 – The season’s enthusiasm will peak in Week 5 as this will feature two heavyweights in the Louisville Cardinals, who are still unbeaten, and the Notre Dame Fighting Irish, who have one loss. Both teams began the season successfully; Louisville is yet to lose a match after three games, while Notre Dame has managed to recover from an early start. This match has been highly marketable, earning the name ‘game of the week’ for several reasons; it matters on the standings and for those who love wagering in top casino sites, especially with grand wagers in this particular matchup.

Louisville Cardinals vs. Notre Dame Fighting Irish 9/28/24

When:Saturday, September 28, 2024, at 3:30 PM ET
Where:Notre Dame Stadium
TV:PEAC
Stream:Sofascore
Louisville Cardinals vs. Notre Dame Fighting Irish 9/28/24
TeamSP/RLTOTALML
Cardinals+9.5 (-110)48.5 over (-110)+270Bet Now on this Game
Fighting Irish-9.5 (-110)48.5 under (-112)-350
Bet Now on this Game

Unreal catch 🤯🤯🤯#GoCards pic.twitter.com/NmPtzauLaM

— Louisville Football (@LouisvilleFB) September 24, 2024

The recent betting lines depict the Notre Dame Fighting Irish as underdogs with a -9.5 spread, placing stronger emphasis on beating the spread against the Cardinals. The total points line is of a peg of 48.5, with a slight overlap of the line giving the Odds on Over, representing expectations of a game with fireworks. Bettors should take these odds seriously, as the Cardinals have all along outperformed the expectations of the Independent set of teams.

Tyler Shough QB vs. Riley Leonard QB

Tyler Shough has been sensational for the Cardinals football in his debut with a passer rating of the season 197.1, gaining 850 passing yards, scoring 8 touchdowns, and clocking a completion percentage of 68.4%. His ability to make accurate long-range throws without getting intercepted has been one of the key components of Louisville’s offense. It would be crucial for Shough to be effective in the pocket against the Notre Dame defense, which has been exposed against better quarterbacks.

On the other hand, Riley Leonard has had a much more modest beginning for the Fighting Irish, sporting a passer rating of 110.3 and throwing only one touchdown and two interceptions. Less than a completed pass per ten attempts (5.7) is risky advertising, which may suggest either a very conservative game plan or a relative inability to do things further awaiting high in such a game in which offense will be paramount. In particular, his game management and turnover issues will be tested against a Louisville defense that takes pride in creating turnovers.

Dynamic Ground Game and Aerial Threats: Louisville’s Offensive Edge

This season, Louisville’s offense has been potent in the air as well as on the ground. With an average of 10.8 yards for every rush, Isaac Brown has an impressive long of 77 who is a game changer on his feet. With a stunning average of 17.5 yards a catch, Ja’Corey Brooks already has 297 yards this season, meaning the Louisville attack has several angles to penetrate Notre Dame’s defense.

Notre Dame’s Balanced Attack: Strategy for Success

Notre Dame counters with Jeremiyah Love, whose 339 rushing yards and 7.4 yards per carry signify a robust ground game that can control the tempo and keep Louisville’s potent offense off the field. Beaux Collins, although not as explosive as Brooks, provides a reliable receiving option for Leonard, and his consistency will be vital for maintaining drives and controlling the clock.

Trends

Louisville Cardinals Betting Trends

The total has gone OVER in 6 of Louisville’s last 8 games.
Louisville is 14-4 SU in their last 18 games.
Louisville is 6-13 SU in their last 19 games on the road.
Cardinals are 5-0 ATS in their last 5 games against an opponent in the Independents (FBS) conference.
Louisville is 8-0 SU in their last 8 games played in September.

Notre Dame Fighting Irish Betting Trends

Notre Dame is 5-2 ATS in their last 7 games.
The total has gone OVER in 7 of Notre Dame’s last 10 games.
Notre Dame is 6-1 SU in their last 7 games.
Fighting Irish are 9-2 SU in their last 11 games at home.
Notre Dame is 13-2 SU in their last 15 games against an opponent in the Atlantic Coast Conference.

Louisville Cardinals vs. Notre Dame Fighting Irish Betting Prediction

Taking a look at the stats and performances on both sides, surely it can be noted that Louisville’s offensive effectiveness, especially how they go over the odds when playing against Independent conference vision statements, gives leeway to the team that the game can be clutch or even an upset secured. Against the spread, they tend to put in strong performances in September, and their ability to stick in the contest makes them a good bet.

To get the best NCAAF free prediction, one could take Louisville at +9.5 because of this team’s trend of scoring lots of points and their very efficient offense. Also, suggest making prop bets on Tyler Shough over passing yards and Isaac Brown to score anytime.

Score Prediction: Louisville 27, Notre Dame 24.

Hilbert Mayer

Sports Writer

Hilbert Mayer is a professional sports writer, betting analyst, and content strategist with over 15 years of experience in the sports industry. Before focusing on sports betting analysis and handicapping, Hilbert worked as a sports writer for various news outlets, covering everything from game recaps to in-depth matchup features. Today, he specializes in MLB, NFL, March Madness, and UFC betting, combining his journalistic background with deep statistical expertise and real-world betting insights. His proven track record, sharp reads, and ability to break down complex matchups make him a trusted voice among both casual bettors and seasoned sharps.

Published on: September 24, 2024
Last updated: March 31, 2025

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